U.S. goverment to sponsor 10 ImClone cancer trials
WASHINGTON The U.S. government will sponsor 10 clinical trials of ImClone Systems’ compound IMC-A12 to treat cancer in the breast, bones, liver, lung, pancreas, and other organs. The compound blocks a receptor on tumor cells that are needed for their development, by acting against a protein called insulin-like growth- factor type 1 receptor, which stops the cells from growing and dividing.
According to Eric Rowinsky, ImClone’s chief medical officer, “Because the insulin-like receptor appears to be active in so many cancers, the co zmpany plans to test IMC-A12 in at least eight types of cancer. The fact that the cancer institute will also conduct 10 trials doubles our capacity right off the bat.”
The company is years away from seeking approval for the drug, but did just begin the second stage of human tests for colon cancer with it.
CIGNA debuts online Rx pricing guide for patients
BLOOMFIELD, Conn. Big insurance and pharmacy benefits management company CIGNA HealthCare has launched an updated version of its online Prescription Drug Price Quote tool for its health and PBM plan members as a price-comparison guide.
The web-based guide is available on the My Plans—Pharmacy page at www.mycigna.com. It offers Cigna Pharmacy members real-time, plan-specific cost comparisons for generic, brand name and available therapeutic alternative medications at 57,000 U.S. pharmacies, according to the health plan giant.
“Rather than relying on national average or regional discount information on retail pharmacy prices, the tool displays side-by-side comparisons of exactly what members would pay for brand named medications, available generics and low cost therapeutic options…based on their benefit plan, as well as the total cost of each medication,” Cigna noted in a statement.
Rexahn receives patent for Zoraxel
ROCKVILLE, Md. Rexahn Pharmaceuticals has received a U.S. Patent for the treatment of sexual dysfunction with its leading drug candidate RX-10100 IR, also known as Zoraxel.
Zoraxel is a drug that enhances neurotransmitters in the brain, both of which play key roles in sexual motivation, erection, and release. This would be the first drug to effect all three phases of sexual activity.
Commenting on today’s news, Chang H. Ahn, Ph.D., Chairman and Chief Executive Officer of Rexahn Pharmaceuticals, noted, “This latest patent coverage for Zoraxel significantly strengthens our patent estate. When added to the four CNS-related U.S. patents and two anti-cancer patents already secured, this represents another key milestone for the Company as we move forward with the clinical development for this promising new drug.”
The company plans to initiate a Phase II trial for Zoraxel by the end of this year.