Supplements with natural S-equol may reduce joint pain, hot flashes in postmenopausal women
CHICAGO A new women’s health, whole soy germ-based nutritional supplement containing natural S-equol reduced the frequency of moderate to severe hot flashes and reduced muscle and joint pain in the first study of its kind among U.S. postmenopausal women, according to peer-reviewed data presented as a poster presentation at the North American Menopause Society Annual Meeting. Also, the first study to report natural S-equol contributions to bone health and a study of natural S-equol safety were presented at NAMS.
“These data from U.S. women expand our knowledge and corroborate previous research in Japanese women about the benefit of a supplement containing the soy-based compound natural S-equol to manage menopausal symptoms, including reducing the frequency of hot flashes and muscle discomfort,” stated Belinda Jenks, co-author of the U.S. women’s and safety studies, and director of scientific affairs and nutrition education at Pharmavite. “This and the other natural S-equol studies are part of the rigorous clinical collaborative program of Pharmavite and Otsuka to develop a supplement containing natural S-equol.”
S-equol is a compound resulting from the natural metabolism of daidzein, an isoflavone found in whole soybeans. Not everyone can produce S-equol after soy consumption, as the production depends on the types of bacteria present in the large intestine and may be influenced by the amount of soy consumed. About 50% of Asians and 20% to 30% of North Americans and Europeans, who in general consume less soy than Asians, have the ability to produce S-equol. Research indicated that Japanese women have milder menopausal symptoms in those who are S-equol producers compared with nonproducers.
All of the studies presented at NAMS used supplement tablets that contained natural S-equol. The SE5-OH is the product of fermentation of whole soy germ by the bacterial strain Lactococcus 20-92. The process results in the conversion of the daidzein to S-equol. SE5-OH is created under current good manufacturing practices. Following fermentation, the bacteria undergo heat denaturation and are deactivated. The process is designed to produce a natural S-equol rich product, or nutraceutical ingredient. The ingredient has self-affirmed GRAS status.
Otsuka Pharmaceutical supported all of the studies. Complete reports of data from each study will be submitted for peer-review publication, the companies stated.
GNC highlights endurance selection
PITTSBURGH GNC on Thursday announced it would highlight its new “Endurance Wall,” which includes as many as 50 SKUs, at two upcoming endurance events.
“The GNC endurance selection is an amazing array of products designed to meet the specific needs of serious athletes across all sports and activities. No matter what their level of experience, GNC has the right product,” stated Tom Dowd, EVP store operations and development.
The new wall will house the on-course drinks for the Ironman World Championship in Kona, Hawaii, on Oct. 9, and from the Bank of America Chicago Marathon on Oct. 10.
“GNC supports a wide range of athletic events around the country, but these two events symbolize the GNC Live Well premise –– that all athletes, whether professionals or serious amateurs, can participate in open events that provide an opportunity for them to demonstrate that their training, with its highs and lows, is worth it all,” stated Dave Sims, GNC VP direct marketing and two-time Hawaii Ironman participant.
In Kona, the PowerBar Ironman Perform is the on-course drink for the race. GNC’s Kona store is only two blocks from the start/finish line and the bike and run components of the race go past it on the way out and coming back. More than 1,800 participants are expected in the Hawaii Ironman event, with thousands more cheering them on.
In Chicago, Gatorade’s G Series Pro 02 endurance formula is the on-course drink for the 33rd running of the marathon. In addition to on-course availability, marathoners and spectators alike will be able to find G Series Pro 02 at GNC stores in the area. As well as the thousands of spectators in downtown Chicago, there will be 38,000 runners, including more than 20,000 from outside Illinois.
Professional Therapy MuscleCare gets ECRM best new product award
LAS VEGAS Professional Therapy MuscleCare last month was awarded “best new product” at the ECRM Health Management EPPS held here. The award, sponsored by Drug Store News, is presented to the manufacturer that collects the most “best new product” votes from retailers attending the event.
As part of its initial rollout, MuscleCare has penned a sponsorship deal with the International Federation of Sports Chiropractic, a group of sports chiropractors from 30 countries that treat Olympic and nationally ranked athletes.
The company fields two topical pain-relief products — topical Professional Therapy MuscleCare extra-strength roll-on gel and Professional Therapy MuscleCare ointment — and presently has distribution through Duane Reade and CVS.com. The products contain camphor and menthol to relax tissue and increase the flow of healthy blood, and nutrients in order to reset the muscle to its normal resting length and promote healing.
"The topical pain-relief industry has long been lacking in safety and efficacy, and I have gone to great lengths and conducted a thorough clinical study to change that," stated Chris Oswald, CEO of Professional Therapy MuscleCare, when debuting the product earlier this year.
The retail price is $19.99 for the roll-on gel and $25.99 for the ointment.