Study: Vitamin D supplementation helps people with lupus erythematosus
LONDON — Vitamin D supplementation could be considered an immunomodulatory agent for systemic lupus erythematosus, an autoimmune disease characterized not only by skin, joint, neurological and renal symptoms, but also by inflammation of tissue linings in the body, according to a new clinical study published Tuesday in BioMedCentral’s open access journal Arthritis Research and Therapy.
An immunomodulatory agent has an effect on the immune system.
In a prospective clinical trial, Nathalie Costedoat-Chalumeau and colleagues set out to evaluate the safety and immunological effects of vitamin D supplementation in 20 SLE patients with low vitamin D levels. They observed these patients over six months and found that vitamin D was not only well-tolerated but, more importantly, there also were no SLE flare-ups during the follow-up period. The authors found that no modification of existing immunosuppressant drugs was needed, nor any new drugs initiated.
Costedoat-Chalumeau stated that the findings confirm that vitamin D may also play other roles in the immune system.
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Study: Out of 20 hand sanitizer brands, Purell only one to deliver on FDA monograph
AKRON, Ohio — Gojo Industries on Wednesday announced the results of a series of independent lab studies testing the ability of instant hand sanitizers to meet Food and Drug Administration Healthcare Personnel Handwash germ kill requirements at various dosage levels. The studies, which included more than 20 different hand sanitizers, concluded that the patent-pending Purell Advanced Instant Hand Sanitizer formulation is the only one to meet FDA germ kill requirements with a single 1.2-mL dispense. All other hand sanitizers in the tests failed to meet performance requirements at a 2-mL dose, even when they contained a higher percentage of alcohol.
"Whether in a workplace, school, healthcare facility or a public setting like a restaurant, casino or health club, people have an expectation of high performance when hand sanitizer is provided," stated Tim Dye, Gojo North American business general manager and VP. "Our newest dispensers, the Purell ADX and LTX systems, are designed to deliver 1.2 mL of hand sanitizer, providing users with the assurance that they are getting the right amount of product for effective germ kill every time."
Purell Advanced Instant Hand Sanitizer formulations contain a patent-pending blend of ingredients that maximize the impact of alcohol on bacteria while maintaining skin moisture for optimal skin health. A blend of four different skin conditioners moisturize skin and continue to promote skin health with repeated use, the company stated.
Additionally, Gojo announced the introduction of the new Purell LTX Touch Free Dispensing System. It’s product innovation across a category that hasn’t seen much product innovation in the past few years. The dispensers are available in solid white or in black with a brushed chrome finish. Two sizes are available: a high-capacity 1,200-mL system for high-traffic locations; and a compact, 700-mL system for areas where space is limited.
Really, A study done by Gojo finds that only Gojo is effective? There are no references to the study? Looks much more like a political ad than a scientific article to me.
JAMA: Supplementing with a daily multivitamin reduces total cancer incidence
CHICAGO — In a randomized trial that included nearly 15,000 male physicians and started in 1997, long-term daily multivitamin use resulted in a modest, but statistically significant, reduction in cancer after more than a decade of treatment and follow-up, according to a study appearing in JAMA that was released Wednesday. The multivitamin used in the study was Pfizer’s Centrum Silver.
“Multivitamins are the most common dietary supplement, regularly taken by at least one-third of U.S. adults," wrote Michael Gaziano of Harvard Medical School. "The traditional role of a daily multivitamin is to prevent nutritional deficiency. The combination of essential vitamins and minerals contained in multivitamins may mirror healthier dietary patterns, such as fruit and vegetable intake, which have been modestly and inversely associated with cancer risk in some, but not all, epidemiologic studies," he continued.
According to the Council for Responsible Nutrition, 52% of Americans take multivitamins, with 42% doing so regularly. Among physicians, 72% personally use dietary supplements, with multivitamins being the most prevalent supplement in this population.
Analysis of the data indicated that men taking a multivitamin, versus placebo, had a modest 8% reduction in total cancer incidence. However, the researchers found no effect of a multivitamin on prostate cancer. “The reduction in total cancer risk … argues that the broader combination of low-dose vitamins and minerals contained in the multivitamin, rather than an emphasis on previously tested high-dose vitamins and mineral trials, may be paramount for cancer prevention," Gaziano wrote.
“This study reinforces the value of long-term consistent use of a daily multivitamin as a convenient and affordable insurance policy for good health,” stated Duffy MacKay, VP scientific and regulatory affairs for the Council for Responsible Nutrition. Not only did this study provide good news for the supplement industry and its consumers, but it also provided another reminder that science should be viewed in the context of the full body of scientific literature, MacKay added.
"This study … demonstrates the role of accessible and affordable consumer health products like multivitamins in cancer prevention," stated Scott Melville, president and CEO for the Consumer Healthcare Products Association. "Now more than ever, consumers should strive to maintain a healthy lifestyle with a balanced diet and exercise, and can continue to rely on vitamins to fill nutritional gaps and enhance health."
The researchers noted that total cancer rates in their trial were likely influenced by the increased surveillance for prostate-specific antigen and subsequent diagnoses of prostate cancer during follow-up starting in the late 1990s. “Approximately half of all confirmed cancers … were prostate cancer, of which the vast majority were earlier stage, lower grade prostate cancer with high survival rates. The significant reduction in total cancer minus prostate cancer suggests that daily multivitamin use may have a greater benefit on more clinically relevant cancer diagnoses," Gaziano noted.
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