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Study shows 50% reduction of myeloma among patients

BY Alaric DeArment

ANN ARBOR, Mich. — A new three-drug combination may work as a front-line treatment for cancer of the plasma cells, according to an early-stage clinical study.

Researchers at the University of Michigan Comprehensive Cancer Center combined Onyx Pharmaceuticals’ drug carfilzomib with Celgene’s Revlimid (lenalidomide) and a low dose of dexamethasone in patients with myeloma. All participants in the study showed a reduction of their disease of at least 50%. Results of the study were presented Tuesday at the American Society of Hematology’s annual meeting.

“The combination treatment appears to deliver everything we expected and more,” Comprehensive Cancer Center multiple myeloma program director Andrzej Jakubowiak said in a statement. “We have seen no neurotoxicity and fantastic efficacy, the best reported to date.”

According to news reports, Onyx plans to file for regulatory approval of carfilzomib in the middle of next year.

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Tops opens first stand-alone gas station

BY Alaric DeArment

WILLIAMSVILLE, N.Y. — Supermarket retailer Tops Friendly Markets has opened its first stand-alone gas station at the site of a former Valero gas station, the chain said.

Tops, which operates 132 supermarkets in upstate New York and northern Pennsylvania, said the gas station has six pumps and a 1,600-sq.-ft. convenience store, rebranded as Tops Fresh Xpress.

“Ideally, we’d like to sell fuel on-site at all existing Tops stores,” Tops president and CEO Frank Curci stated. “When that isn’t possible, we’ll carefully consider other opportunities to best serve our customers.”

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Carla Cooper named CEO of Daymon Worldwide

BY Allison Cerra

STAMFORD, Conn. — A maker of private-brand products has appointed a new CEO.

Daymon Worldwide said consumer packaged goods veteran Carla Cooper, who has served on the company’s board since 2009, will replace co-founder Milton Sender, who will retain his position as chairman of the board.

Prior to joining Daymon Worldwide, Cooper served in senior management positions at such companies as Coca-Cola, PepsiCo, Procter & Gamble and Kellogg.

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