Study notes possible risk of PPI use
ALEXANDRIA, Va. Despite being highly effective and beneficial for many patients, unexpected consequences are emerging in patients who are prescribed proton pump inhibitors for reflux diseases, according to a new commentary published in the November 2009 issue of Otolaryngology – Head and Neck Surgery.
According to the authors, gastroesophageal reflux and laryngopharyngeal reflux are diseases that have undergone a remarkable growth in public health relevance over the last 20 years. While it has been known historically that more than 50% of adults in Western countries have occasional symptoms of reflux, there has been a more than four-fold increase in how many patients seek medical care for their symptoms.
According to the authors, there is a growing body of literature demonstrating that acid is not the only causal agent of tissue damage in reflux disease, and that PPIs, which inhibits acid production in the stomach, are not effective at treating all cases of GERD and LPR.
The authors also suggested that PPIs are associated with rates of hip fractures, possibly related to altered calcium absorption; a possible but yet unproven altered vitamin B12 and iron absorption, related to alteration of the gastric pH; increased odds of acquiring nosocomial Clostridium difficile-associated diarrhea; and increased odds of contracting community-acquired pneumonia.
Roche launches skin design challenge for meters
INDIANAPOLIS Roche Diabetes Care on Thursday announced the launch of the Born in the USA Meter Skin Design Challenge, where diabetics can create a custom skin for their Accu-Chek Aviva blood glucose meter at www.rockmymeter.com.
“We are excited to announce this fun skin design challenge, and encourage both former visitors to the site, as well as newcomers, to try their hand at designing an Accu-Chek Aviva personalized skin design,” stated Roche VP marketing Dan Kane. “The launch of www.rockmymeter.com earlier in the year was such a hit, we decided to create some friendly competition. We’re hopeful some of our Accu-Chek fans will show their pride at using a meter that’s manufactured in the United States by creating fun, patriotic skins that may be included in future Accu-Chek Aviva skin offerings.”
The deadline for consumers to enter a customized skin for consideration is Feb. 28, 2010.
All site visitors will have the opportunity to vote for their favorite designs. From the top 50 vote-getters, Roche Diabetes Care’s marketing management will choose four winners, and those four skins actually will replace four of the five current skins designs in a currently available meter skins pack.
Researchers find link between gut bacteria, obesity
ST. LOUIS A recent study has found that gut bacteria can lead to obesity.
Researchers at the Washington University School of Medicine in St. Louis found that after transplanting human microbes into mice, and taking the mice off of a low-fat diet to one made up of high fat and sugars, the microbial makeup of the mice changed within 24 hours. The content of the diet changed the composition of gut bacteria, thus making them rapidly gain weight.
Scientists stress that there are many factors that play a role in weight gain, but this discovery may help scientists have a better understanding and perhaps treat the problem of obesity.