HEALTH

Study: Fish oil may aid dental health

BY Michael Johnsen

ST. LOUIS, Mo. Supplementing with fish oils could help improve gum health, according to research published in the November issue of the Journal of the American Dietetic Association. Researchers from Harvard Medical School and Harvard School of Public Health found that dietary intake of polyunsaturated fatty acids like fish oil, known to have anti-inflammatory properties, shows promise for the effective treatment and prevention of periodontitis, otherwise known as gum disease.

"We found that n-3 fatty acid intake, particularly docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA), are inversely associated with periodontitis in the U.S. population," said researcher Asghar Naqvi. "To date, the treatment of periodontitis has primarily involved mechanical cleaning and local antibiotic application. Thus, a dietary therapy, if effective, might be a less expensive and safer method for the prevention and treatment of periodontitis. Given the evidence indicating a role for n-3 fatty acids in other chronic inflammatory conditions, it is possible that treating periodontitis with n-3 fatty acids could have the added benefit of preventing other chronic diseases associated with inflammation, including stroke as well."

 

The study involved more than 9,000 adults who participated in NHANES between 1999 and 2004 who had received dental examinations. Dietary DHA, EPA and LNA intake were estimated from 24-hour food recall interviews, and data regarding supplementary use of PUFAs were captured as well. The NHANES study also collected extensive demographic, ethnic, educational and socioeconomic data, allowing the researchers to take other factors into consideration that might obscure the results.

 

 

The prevalence of periodontitis in the study sample was 8.2%. There was an approximately 20% reduction in periodontitis prevalence in those subjects who consumed the highest amount of dietary DHA. The reduction correlated with EPA was smaller, while the correlation to LNA was not statistically significant.

 

 

Foods that contain significant amounts of polyunsaturated fats include fatty fish like salmon, as well as peanut butter, margarine and nuts.

 

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Strativa enters license, supply agreement with Sobi

BY Alaric DeArment

WOODCLIFF LAKE, N.J. Strativa Pharmaceuticals is working with a Swedish drug maker to develop and commercialize a prescription vitamin supplement, Strativa said Tuesday.

 

The company said it had signed a license and supply agreement with Swedish Orphan Biovitrum, also known as Sobi, concerning European rights to Strativa’s Nascobal (cyanocobalamin), a vitamin B12 nasal spray.

 

 

The supplement is approved for treating vitamin B12 deficiency, designed as a once-weekly alternative to injections. Vitamin B12 deficiency usually results from pernicious anemia, a strict vegetarian diet and poor absorption of the nutrient resulting from such medical conditions as HIV infection, Crohn’s disease, multiple sclerosis and gastrectomy.

 

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PerformRx receives PBM accreditation from URAC

BY Allison Cerra

PHILADELPHIA A full-service pharmacy benefit manager received its second accreditation from an independent, nonprofit healthcare-accrediting organization.

PerformRx said that its pharmacy benefit management accreditation from URAC indicated that PerformRx’s PBM business demonstrated a commitment to quality services. “This accreditation serves as a clear sign that PerformRx is committed to providing the best possible service to our existing and future customers,” said Mesfin Tegenu, PerformRx president. “The URAC evaluation is an incredibly rigorous process that evaluates the organization at all levels, and to wear the URAC seal is a mark of distinction for our company.”

In conjunction with its PBM accreditation, PerformRx also applied for URAC’s drug therapy management accreditation. PerformRx’s DTM program improves therapeutic outcomes for members by evaluating drug dose, method of delivery, cost effectiveness and other factors, the company said, adding that obtaining the DTM accreditation will allow PerformRx to demonstrate the high quality and effectiveness of its DTM program.

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