Study finds link between insomnia, high insulin resistance among diabetics
NEW YORK — Diabetics that have trouble sleeping likely experience high insulin resistance and have a more difficult time controlling the disease, according to study findings published in the June issue of Diabetes Care.
Researchers said they monitored the sleep of 40 subjects with diabetes for a duration of six nights and also measured the subjects’ insulin and glucose levels during clinical examinations. The subjects also reported if they generally suffered from symptoms of such sleep disturbances as insomnia, snoring or sleep apnea.
Among the diabetics, poor sleepers had 23% higher blood-glucose levels in the morning, as well as 48% higher blood insulin levels. Using these numbers to estimate a person’s insulin resistance, the researchers found that poor sleepers with diabetes had 82% higher insulin resistance than normal sleepers with diabetes.
The data was collected as part of the CARDIA study, an ongoing longitudinal study of the heart health that is supported by the National Heart, Lung and Blood Institute. It has tracked thousands of people for more than 20 years, study investigators said.
"Poor sleep quality in people with diabetes was associated with worse control of their blood-glucose levels," said Kristen Knutson, assistant professor of medicine and lead author of the study. "People who have a hard time controlling their blood-glucose levels have a greater risk of complications, they have a reduced quality of life and they have a reduced life expectancy."
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These are important findings and offer a relatively simpler and solvable issue, insomnia, as a means of improved blood glucose levels, reduction in complications and extended life expectancy for diabetic patients. Actigraphy, from Fatigue Science, may offer an objective, simple, affordable technology for patients to monitor the quality and quantity of their sleep.
Pharmacy’s role in emergency preparedness underscored in statement to House subcommittee
ALEXANDRIA — Pharmacies play a critical role in emergency preparedness. That was the key message in a statement issued this week by the National Association of Chain Drug Stores to the House of Representatives’ Homeland Security Subcommittee on Emergency Preparedness, Response and Communications.
The subcommittee held a hearing this week, titled "Taking Measure of Countermeasures: A Review of Efforts to Protect the Homeland Through Distribution and Dispensing of CBRN [chemical, biological, radiological or nuclear] Medical Countermeasures."
In the statement, NACDS outlined the ways in which pharmacies are equipped and stand ready to assist policymakers and public health officials at all levels of government in ensuring convenient access to countermeasures in a medically relevant time frame following an emergency.
NACDS discussed pharmacy’s role in extending the reach of public health during the aftermath of emergencies, such as Hurricane Katrina and during the 2009 H1N1 influenza pandemic. During these types of situations, pharmacists performed a range of services for patients and worked cooperatively with state and local partners to ensure access to high-quality patient care.
"Pharmacists have performed a range of services to targeted patient populations following emergencies, including dispensing countermeasures, administering vaccines, patient screening and triage, education of the public and monitoring for adverse events," NACDS highlighted in the statement. "Pharmacies have existing technological infrastructures that can be leveraged to triage patients, have a lot space to accommodate surges in patient demand and sell personal protective equipment and medical supplies that may also be important in preventing or treating CBRN threats."
"As the face of neighborhood health care, community pharmacies remain committed to assist public health efforts to protect our citizens through convenient access to countermeasures. We look forward to working with Congress and the public health community to ensure the nation’s community pharmacies are used to the greatest extent possible," the statement concluded.
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PhRMA: More than 850 medicines in development for diseases that disproportionately affect women
WASHINGTON — More than 800 drugs are in development for diseases that affect women, according to a pharmaceutical industry lobbying group.
The Pharmaceutical Research and Manufacturers of America released a list of 851 treatments for diseases that disproportionately or exclusively affect women, such as rheumatoid arthritis, multiple sclerosis, depression, osteoporosis and age-related macular degeneration. All the medicines are either in clinical trials or awaiting review by the Food and Drug Administration, PhRMA said. About 90% of the people in the United States with lupus, migraines and fibromyalgia are women, while women having heart attacks also experience markedly different symptoms from men.
“As recently as a couple [of] decades ago, there was a basic assumption that what was good medically for men was good for women in almost every case,” PhRMA president and CEO John Castellani said. “Today, our increasing knowledge of the less obvious differences between men and women is providing great promise for new and better treatments that will benefit both sexes.”
The drugs in development include 139 for cancers, 38 for multiple sclerosis and 22 for osteoporosis.
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