Shire says nasal administration won’t increase abuse of ADHD drug
PHILADELPHIA Administration of an attention-deficit hyperactivity disorder drug through the nose does not appear to increase the risk of people abusing it, according to data released by the drug’s manufacturer.
British drug maker Shire said when adults received Vyvanse (lisdexamfetamine dimesylate) intranasally in the form of a solution, their rate and exposure to d-amphetamine, the drug’s active ingredient, was similar to when they took the drug in a capsule. The drug is currently approved only in capsule form.
“This research is important because the route of administration of a drug may affect the rate and extent of absorption, which in turn may affect the risk of abuse,” Shire VP global clinical pharmacology and pharmacokinetics Patrick Martin said in a statement. “However, in this study, absorption of Vyvanse through the nose did not result in a rapid rise in d-amphetamine levels.”
FDA approves Diuril generic
SCHAUMBURG, Ill. The Food and Drug Administration has approved the first generic version of an injected drug for hypertension.
APP Pharmaceuticals announced the approval of chlorothiazide sodium, which it plans to launch in fourth quarter 2009.
The drug is a generic version of Lundbeck Pharmaceuticals’ Diuril, a diuretic used for treating hypertension and fluid retention in patients with congestive heart failure, cirrhosis of the liver, kidney disorders and edema.
Diuril had sales of $51 million in 2008, according to IMS Health data.
CVS launches interactive Web and mobile features online
WOONSOCKET, R.I. CVS Caremark is providing customers with more tools to help them manage prescriptions, access health information and save money through new interactive Web and mobile features at CVS.com.
The new CVS.com Mobile (m.cvs.com) provides customers with an on-the-go pharmacy resource to refill, transfer and manage prescriptions. They can also find store locations and take advantage of such features as Savings Central and Virtual Gift Card.
“The new CVS.com Mobile site is a helpful resource for customers who rely on real-time access to their medication history, drug information or simply need help with driving directions or a phone number to a nearby CVS/pharmacy or MinuteClinic,” stated Helena Foulkes, CMO of CVS Caremark. “Additionally, Savings Central provides users with a one-stop online destination for information on health care savings, deals and discounts. These new features, along with the addition of Virtual Gift Cards, are examples of how we are continuing to enhance the customer experience, both in-store and online.”
By visiting CVS.com Mobile, patients can access the Drug Information Center, which allows rapid access to details about medication management, including instructions for use, dosing information, side effects and relevant safety warnings.
Meanwhile, the new Savings Central combines information about healthcare savings with other deals and discounts in one location. By clicking on the “Savings Central” tab, budget-conscious customers can find ways to save money through coupons and special promotions. There are tabbed pages detailing information on such topics as pharmacy savings, circulars, in-store coupons, and online sales and specials.