PHARMACY

Nipro, NeuroMetrix collaborate to market NC-stat DPNCheck

BY Allison Cerra

WALTHAM, Mass. — Nipro Diagnostics and NeuroMetrix have teamed up to market a point-of-care test that is designed to evaluate such systemic neuropathies as diabetic peripheral neuropathy.

Nipro and NeuroMetrix said the NC-stat DPNCheck test, developed by NeuroMetrix, could offer a cost-effective approach to detecting and monitoring DPN, which affects more than half of people with diabetes and could lead to such conditions as foot ulcers and limb amputation.

The companies currently are evaluating opportunities for the NC-stat DPNCheck in retail medical clinics.

Nipro and NeuroMetrix are slated to debut the test at the annual conference of the American Diabetes Association, which will be held from June 24 to 28.

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Liraglutide may prompt optimal blood-glucose levels in Type 1 diabetics

BY Allison Cerra

BUFFALO, N.Y. — A popular Type 2 diabetes treatment may help Type 1 diabetics achieve control of their blood-glucose levels, according to a small, observational study conducted at the University of Buffalo.

The study examined 14 adult Type 1 diabetics on insulin and added injectable Type 2 diabetes medication liraglutide to their medication regimen for periods ranging from one week to 24 weeks. Although all of the Type 1 diabetes patients had optimal blood-glucose levels at the beginning of the study, lead author Paresh Dandona, professor of medicine at the University of Buffalo’s School of Medicine and Biomedical Sciences, said that some patients experience "glycemic excursions," in which blood-glucose measures reach hypoglycemic or hyperglycemic levels.

Dandona and colleagues found, however, that within one to two days of beginning treatment with liraglutide, such glycemic excursions were offset but reversed just as quickly when treatment was discontinued, revealing that liraglutide likely was responsible for these effects and could be an effective add-on therapy to insulin.

"The addition of liraglutide to insulin therapy in these well-controlled Type 1 diabetics resulted in a significant and rapid reduction in glycemic excursions and, as a consequence, a rapid reduction in the amount of insulin they needed to take," Dandona said. "We will be investigating in detail the hypothesis that it is liraglutide’s ability to suppress glucagon that significantly reduces the wide swings in blood glucose levels that Type 1 diabetics — even those with very good glucose control — live with everyday."

The research has been published online ahead of print in the European Journal of Endocrinology. It also was recently presented at the annual meeting of the Endocrine Society in Boston.

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FDA rejects Teva’s request to block Watson’s generic Seasonique

BY Alaric DeArment

PARSIPPANY, N.J. — A federal court has rejected Teva Pharmaceutical Industries’ efforts to prevent Watson from launching a generic version of one of its drugs, Watson said Friday.

The U.S. District Court for the District of Nevada denied Duramed Pharmaceuticals’ request for an injunction to keep Watson’s generic version of the contraceptive Seasonique (levonorgestrel and ethinyl estradiol 0.15 mg/0.03 mg) and ethinyl estradiol 0.01 mg from being launched.

Seasonique is made by Teva Women’s Health, the successor of Duramed.

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