HEALTH

McNeil Consumer Healthcare expands Visine line

BY Michael Johnsen

MORRIS PLAINS, N.J. McNeil Consumer Healthcare on Wednesday announced the introduction of Visine Totality Multi-Symptom Relief — a new eye drop formulated to relieve the seven symptoms associated with eye irritation, including red, burning, watery, itchy, gritty, dry and irritated eyes.

The company also introduced Ultra-soft Visine Total Eye Soothing Wipes for cleansing the area around the eyes, removing make-up, debris and irritants like dust and pollen. The ophthalmologist- and dermatologist- tested wipes feature a blend of eight moisturizers, a cooling agent, and a gentle cleanser (Coco-Glucoside) derived from coconut and fruit sugars to sweep away debris. Safe for sensitive eyes and contact lens wearers, the wipes gently glide around the eyes to soothe the area and deliver clean, fresh, makeup-free eyes.

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Scientists uncover immune system’s role in bone loss

BY Michael Johnsen

LOS ANGELES A new UCLA study sheds light on the link between high cholesterol and osteoporosis and identifies a new way that the body’s immune cells play a role in bone loss, the University announced Monday.

Published Aug. 20 in the journal Clinical Immunology, the research could lead to new immune-based approaches for treating osteoporosis, authors of the study noted. Affecting 10 million Americans, the disease causes fragile bones and increases the risk of fractures, resulting in lost independence and mobility.

Scientists have long recognized the relationship between high cholesterol and osteoporosis, but pinpointing the exact mechanism connecting the two has proved elusive.

“We’ve known that osteoporosis patients have higher cholesterol levels, more severe clogging of the heart arteries and increased risk of stroke. We also knew that drugs that lower cholesterol reduce bone fractures, too,” explained Rita Effros, professor of pathology at the David Geffen School of Medicine at UCLA. “What we didn’t understand was why.”

In the study, UCLA researchers focused on low-density lipoprotein (LDL) and examined how high levels of oxidized LDL affect bone and whether a type of immune cell called a T cell plays a role in the process.

Using blood samples from healthy human volunteers, the team isolated the participants’ T cells and cultured them in a dish. Half of the T cells were combined with normal LDL – the rest was combined with oxidized LDL. The scientists stimulated half of the T cells to mimic an immune response and left the other half alone.

“Both the resting and the activated T cells started churning out a chemical that stimulates cells whose sole purpose is to destroy bone,” Effros said. Called RANKL, the chemical is involved in immune response and bone physiology.

When Effros and her colleagues tested the T cells of the mice on the high-fat diet, they discovered that the cells acted differently than those of the mice on a normal diet.

The T cells switched on the gene that produces RANKL. The chemical also appeared in the animals’ bloodstream, suggesting that the cellular activity contributed to their bone loss.

“It’s normal for our T cells to produce small amounts of RANKL during an immune response,” explained Effros. “But when RANKL is manufactured for long periods or at the wrong time, it results in excessive bone damage.”

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CDC, Reckitt Benckiser develop site to promote good health, hygiene

BY DSN STAFF

NEW YORK On the surface, this news highlights how serious the Centers for Disease Control and Prevention take that “prevention” piece of their title. The fact of the matter is the novel H1N1 influenza pandemic, the virus that ran rampant in the spring, giving the United States a little taste of what could come, will be the top billing this coming cough-cold-flu season. To date, the virus has not mutated in the past few months as it ran its course through the influenza season of the southern hemisphere, which means that Americans can expect more of the same here — an influenza strain that produces illness severity comparable to the seasonal flu but that favors younger people because they have no antibodies in reserve against this novel H1N1 virus.

Younger people not only means the twenty- and thirtysomethings in the workforce, it also means their school-age children. And given that children are oftentimes blamed for spreading colds and flu in a typical year, it only goes to reason that children may be a good spreader of the H1N1 pandemic virus, too. With this partnership, the CDC is making a robust effort in educating both children and their parents in proper cold/flu etiquette, because the cheapest way to nip this bug from the get-go is to inhibit its spread.

Going one level deeper, it also shows how quickly today’s administration will turn to private business in an attempt “to get things done.” The assumption here is that it’s not the CDC putting up the funds to launch this Web site, but Reckitt Benckiser. And in turn, Reckitt Benckiser gets a very credible driver around its Lysol disinfectant brand.

That bodes well for retail pharmacy and the healthcare companies that supply them. Because it bears a recognition what the private sector brings to the table — ready access to consumers who may be more apt to pay attention when the credibility of government agencies like CDC is married to the credibility associated with a venerable brand. Today it’s Reckitt Benckiser’s Lysol. Tomorrow it could very well be CVS or Walgreens.

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