Mayo Clinic study notes St. John’s wort ineffective in treating IBS
ROCHESTER, Minn. A Mayo Clinic research study published in the January issue of The American Journal of Gastroenterology found that St. John’s wort is not an effective treatment for irritable bowel syndrome.
While antidepressants are frequently used to treat IBS, to date, no study has examined the success of using the herbal supplement St. John’s wort in treating IBS.
“Our study investigated if herbal antidepressants such as St. John’s wort could benefit irritable bowel disease patients,” says Yuri Saito, M.D., M.P.H., gastroenterologist and lead physician scientist on the study. “Several of the chemical neurotransmitters that are in the brain are also in the colon. Therefore, it’s been thought that antidepressants may affect sensation in the colon in a similar way to how they affect sensation in the brain. Our goal was to evaluate the usefulness of St John’s wort in treating IBS.”
In this placebo-controlled trial, 70 participants with IBS were randomized where half the patients received St. John’s wort and the other half received a placebo for three months. In all, 86 percent of the participants were women, and the median age was 42 years. After three months of observing symptoms such as stomach pain, diarrhea, constipation and bloating, Mayo researchers found that the placebo group had a better response than the group taking the herbal supplement, St. John’s wort.
“Because people tend to struggle with IBS for several years, patients are really looking for inexpensive, over-the-counter treatments such as St. John’s wort,” Saito said. “Unfortunately, our study showed that St. John’s wort was not successful in helping IBS patients.”
St. John’s wort is an herbal supplement derived from the St. John’s wort plant. It has been shown to be helpful in such several medical conditions as depression, as well as other pain syndromes. Research has shown it to be as effective as conventional, prescription antidepressants in treating mild to moderate depression.
“The challenge with IBS is that there is no cure, no one treatment tends to be wholly effective and some treatments come with significant side effects,” Saito said. “However, well-designed studies of herbal supplements are important so that physicians and patients can make informed decisions about which supplements to recommend or try. Studies of alternative treatments are generally lacking and patients are forced to use a ‘trial and error’ approach to over-the-counter treatments for their IBS.”
IBS is a common disorder that affects the colon and commonly causes cramping, abdominal pain, bloating, gas, diarrhea and constipation. Approximately 58 million people struggle with IBS, mostly women.
Tylenol Arthritis caplet recall becomes a bigger headache
NEW YORK Johnson & Johnson has expanded its voluntary recall of Tylenol Arthritis caplets in the wake of consumer reports of a moldy smell that can cause nausea and sickness. The recall now includes all product lots of the Arthritis Pain caplet 100-count bottles with the red EZ-Open cap.
Prior to this, the company had recalled five lots of the product in November, citing similar reasons, with user complaints of nausea, stomach pain, vomiting and diarrhea.
According to J&J, the odor is coming from trace amounts of 2,4,6-tribromoanisole — a chemical used to treat wooden pallets that transport and store packaging materials — which is believed to be the result from the breakdown of another chemical used in the manufacture of the drug.
To date, the side effects have been “temporary and non-serious,” although the health effects of the compound have not been studied.
The recall only affects the specific lots reported, and does not extend to any other Tylenol pain products.
J&J is moving its production of Tylenol Arthritis Pain caplets 100-count to another plant, and plans to reintroduce the product in January.
J&J is advising consumers seeking a refund or replacement to call (888) 222-6036.
P&G adds new products to Vicks DayQuil line
CINCINNATI Procter & Gamble on Wedneday introduced Vicks DayQuil Mucus Control and DayQuil Mucus Control DM. These products, which work for four hours, help loosen and thin mucus.
Vicks DayQuil Mucus Control provides mucus relief, making coughs more productive. In addition, DayQuil Mucus Control DM contains a cough suppressant for combined comfort of thinning mucus and controlling cough.
“When you are sick, your body produces excess mucus, which also becomes thicker and more difficult to clear,” stated Matt Kemme, brand manager, Vicks. “We’ve uncovered an insight that some consumers are restricting their mucus treatment to avoid coughing up phlegm in public,” he said. “The expectorant agent in Vicks DayQuil Mucus Control acts for four hours, helping people control over when and where they expel their mucus out.”
Average retail price ranges between $6.49 and $7.29.