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Lilly ceases clinical research of pomaglumetad methionil as schizophrenia treatment

BY Allison Cerra

INDIANAPOLIS — Eli Lilly has ceased ongoing clinical studies of an investigational treatment for schizophrenia.

The drug maker said that after recently conducting an independent futility analysis, it concluded that the second of Lilly’s two pivotal studies "was unlikely to be positive in its primary efficacy endpoint if enrolled to completion." Additionally, the recently completed phase-2 study, which investigated pomaglumetad methionil (also known as mGlu2/3) as an adjunctive treatment with atypical antipsychotics, did not meet its primary endpoint.

"I’m disappointed in what these results mean for patients with schizophrenia who still are searching for options to treat this terrible illness," said Jan Lundberg, Lilly EVP science and technology, and Lilly Research Labs president. "While there are many challenges in this complex field of research, neuroscience remains a core area of focus at Lilly. Our clinical development pipeline includes nearly a dozen neuroscience molecules being studied to treat illnesses, such as depression, bipolar disorder and cognitive impairment associated with schizophrenia."


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Puffs partners with Dress for Success to help women put best faces forward

BY Allison Cerra

CINCINNATI — A facial tissue brand has partnered with an organization that promotes the economic independence of disadvantaged women.

Puffs announced that it has partnered with Dress for Success to provide beauty makeovers for deserving women across the country. Through Oct. 12, Puffs is hosting a tab on its Facebook page, which will allow people to upload their inspirational quotes, tips and stories on how they put "their best face forward" every day. As fans submit their tip — which will be hosted on a gallery within the tab — Puffs will donate $1 per upload to Dress for Success Worldwide to help promote the economic independence of disadvantaged women. What’s more, with every entry, fans will be entered into a sweepstakes to win 1-of-60 Procter & Gamble beauty baskets, as well as a grand-prize trip to New York for a beauty makeover.

"Like Puffs, Dress for Success aims to help women get a fresh new start in both work and in life," Puffs communications manager Laura Dressman said. "We’re proud to partner with such an uplifting organization and hope fans everywhere engage in the motivating tips on our Facebook page to help us honor the beauty in all women."

Throughout the program, Puffs and Dress for Success also will host local events in Chicago and San Francisco, as well as a finale event in New York, offering Dress for Success clients in attendance wardrobe and beauty makeovers.

"Dress for Success helps provide women with the tools they need to succeed both personally and professionally," Dress for Success Worldwide CEO Joi Gordon said. "Through this exciting new partnership with Puffs, our women will receive the confidence they need to put their best face forward as they re-enter the workforce."

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Sara Lee expands pound cake portfolio

BY Allison Cerra

DOWNERS GROVE, Ill. — Sara Lee has refreshed its pound cake lineup.

The company has revamped its butter pound cake recipe, which now is more moist, and has introduced a lemon-flavored cake. The two varieties are part of a portfolio that also includes the lower-calorie Light and Dreamy pound cake, as well as pound cake slices (which come in original and double chocolate flavors).

The average suggested retail price for the regular size of Sara Lee pound cake products is $3.99. The butter pound cake also is available in family size, which carries an average suggested retail price of $5.39.

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