PHARMACY

Investigation reveals pharmaceutical waste in U.S. waterways

BY Alaric DeArment

NEW YORK An investigation by the Associated Press has found that drug makers in the United States have dumped 271 million or more lbs. of compounds used in pharmaceuticals into waterways, including those that provide drinking water.

The catch is, it’s legal.

AP said that the federal government and industry officials don’t normally keep tabs on how much gets into the water, but it did look at federal records dating back 20 years that give an idea. Because of the lack of testing, it’s unclear how many of those 271 million lbs. come from drug makers and how many come from manufacturers that use such chemicals that appear in drugs as nitroglycerin and lithium, according to AP.

The investigation follows a previous AP investigation that found pharmaceutical contamination in the drinking water of 51 million Americans.

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Vertex reports Q1 earnings

BY Alaric DeArment

CAMBRIDGE, Mass. Vertex Pharmaceuticals ended first quarter 2009 with $869 million in cash, cash equivalents and marketable securities, the company announced Thursday.

The company is conducting a phase 3 study of telaprevir, a protease inhibitor for treating hepatitis C in patients who have not received treatment or for whom other treatments have failed. In March, Vertex started a phase 2a trial of VX-809, a compound designed to treat cystic fibrosis, and it also plans to start trials for the investigational CF drug VX-770 in the United States and Europe.

“With our strong performance in the first quarter, we are well-positioned to drive forward key programs in hepatitis C and cystic fibrosis and to deliver on our 2009 financial projections outlined earlier this year,” Vertex president Matt Emmens said. “Our top priority is to execute on the telaprevir phase 3 program and to prepare for [a new drug application] filing for telaprevir in the second half of 2010.”

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Drug maker’s shares fall after HHS requests regulatory filing

BY Alaric DeArment

NEW YORK A Department of Health and Human Services request that companies bidding on a government contract to provide anthrax vaccines give a regulatory plan to the Food and Drug Administration in 15 days caused shares of one of the companies to fall by 5.5% in afternoon trading on Friday, according to published reports.

The Associated Press reported Thursday that PharmAthene submitted a regulatory filing saying that HHS did not provide sufficient information. The HHS request caused PharmAthene’s shares to fall by 15 cents, to $2.56.

The Annapolis, Md.-based company makes the anthrax vaccine SparVax.

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