BEAUTY CARE

Has a unique ‘skin fingerprint’ unlocked the secret to the fountain of youth?

BY Antoinette Alexander

VANCOUVER, B.C. — Do you ever wonder why some women look much younger than their age? Could it be her genes, does she use a “magic” cream or has she had a cosmetic procedure? Research from Procter & Gamble’s Olay shows how gene expression changes impact the appearance and quality of women’s skin as they age across every decade.

Olay’s Multi-Decade and Ethnicity study reveals biological commonalities among a unique subset of women who look exceptionally younger than their age. In addition, the research found specific gene expression changes that impact the skin aging process during each decade of a woman’s life.
 
The MDE study, which was initiated in 2012, marries genotypic and phenotypic science and examines women in nearly every decade of life – from their 20s to their 70s – and across ethnicities – Caucasian, African, Hispanic and Asian. The study is led by Alexa Kimball, professor of dermatology, Harvard Medical School/Massachusetts General Hospital, and other scientific and analytical research partners in the fields of systems biology, skin biology, and 3D imaging and hormone mapping. For the first time, Olay entered into a collaboration with 23andMe, a personal genetics company, to further understand the genes linked to skin aging and their biological variability across different ethnicities.

The initial findings of this MDE study include data from Caucasian and African research participants. From these, there are two key takeaways that will help determine what’s possible when it comes to cosmetic skin care and looking ageless.

First, there are similarities among women who have not undergone cosmetic procedures but still appear to be “ageless.” Through advanced bioinformatics analysis of approximately 20,000 genes, Olay identified a unique skin fingerprint among these “exceptional skin agers” comprised of around 2,000 genes. They are responsible for a range of key biochemical pathways, including those involved in cellular energy production, cell junction and adhesion processes, skin and moisture barrier formation, DNA repair and replication, and anti-oxidant production. The MDE study found that although we all have these genes in our skin, how strongly these genes are expressed in the skin is distinct in “exceptional skin agers” – and that can be influenced by environmental factors, lifestyle choices and even skin care habits.

“What’s exciting about these findings is that the genes that make up the unique skin fingerprint of ‘exceptional skin agers’ may hold the key to successful aging, and decoding which pathways they affect and why they are acting differently in these women – nature or nurture – can enable Olay researchers to help more women achieve skin that looks like the exception, not the rule at any stage of life,” stated Rosemarie Osborne, P&G Beauty research fellow.

In fact, research conducted in-vitro has confirmed that Olay’s top-performing ingredients, such as Niacinamide (vitamin B3), pal-KTTKS (peptide), Olivem and Lyslastine are key components to address skin aging.
The second key takeaway from these initial findings is that based on the study of a subset of Caucasian women, there are distinct gene expression “tipping points” that occur in each decade as we age:
1.    Decline in antioxidant response (20s)
2.    Decline in skin bioenergy (30s)
3.    Increase in cellular senescence (40s)
4.    Decline in skin barrier function (50s)
5.    Acceleration of all the above (60s)

Olay is continuing to collect and analyze samples from Asian and Hispanic women in their 20s to 70s to broaden the application of the study’s findings. Once completed, the MDE study will have examined female skin aging throughout six distinct decades and across four different ethnicities. In totality, this research positions Olay at the forefront of skin biology research, which may lead to transformative skin care products.

 

keyboard_arrow_downCOMMENTS

Leave a Reply

No comments found

TRENDING STORIES

Polls

Which area of the industry do you think Amazon's entry would shake up the most?
BEAUTY CARE

Connected electric toothbrush maker Kolibree to ramp up growth in North America

BY Antoinette Alexander

NEW YORK — French company Kolibree, makers of a connected electric toothbrush, has secured a round of financing to further its momentum in North America.

Kolibree closed a Series A round of financing at the end of April with venture capital and industrial groups SEB Alliance, Innovacom, Cap Horn Invest and the Dental Investment Group for Health.
 
“Following a successful launch showcasing Kolibree’s innovative disruptive technology at CES (Consumer Electronics Show 2015), Innovacom is excited about our investment in Kolibree to keep the momentum going in North America,” stated Innovacom partner Vincent Deltrieu.

As a result of this new funding, Kolibree is building relationships with growing numbers of dental professionals and consumers across the United States.

“Kolibree’s mission is to reduce the occurrence of oral disease by deploying the latest technology for prevention,” stated Kolibree CEO Thomas Serval.

Kolibree’s interactive approach turns a child’s toothbrushing time from an argument into a game. Connected via Bluetooth to either an IOS or Android device, Kolibree’s Go Pirate (for children) and Coach (for adults) — included in the free Kolibree app — motivate and train users to properly brush their teeth. Kolibree’s 3D motion sensors transmit real-time feedback on the length of time, areas brushed, and how hard the user brushes. Data is stored so parents can easily monitor the whole family’s progress toward developing proper oral care.

Dental practitioners have been a key part of the team during ongoing Kolibree development, making sure the goal of improving oral hygiene is met, the company stated.

 

keyboard_arrow_downCOMMENTS

Leave a Reply

No comments found

TRENDING STORIES

Polls

Which area of the industry do you think Amazon's entry would shake up the most?
BEAUTY CARE

Walgreens brings beauty tips to life through Challenged app

BY Michael Johnsen

NEW YORK — Walgreens is collaborating with the new social competition app Challenged to bring summer beauty tips to life, the company announced Tuesday. Challenged is an app that takes inspiration from last year's viral Ice Bucket Challenge and works to create a social challenge creation and fulfillment experience for users, celebrity influencers, and charities to drive healthy competition and positive social change.
 
Users joining the app today will find it already populated with a challenge from Walgreens, which asks users to bring their best summer beauty tip to life in a 12-second video using either CIRCA Beauty or Nonie Creme Colour Prevails products available exclusively at Walgreens. Beauty expert Lauria Locsmondy of the Walgreens social and content creative team will judge submitted Beauty Challenge videos submitted based on the following criteria:
 
  • Use of CIRCA and/or Colour Prevails items as a primary component of the look;
  • Clear steps to achieve the look; and 
  • The look’s summer relevance
The top submission chosen will win an assorted prize of the best-selling products from the two beauty lines. The 30-day video challenge will run from June 9 through July 8 with the official Walgreens beauty challenge hashtag: #BeautyChallengeContest
 
"Video continues to be a compelling way to tell a great story. Today, more than ever, user-generated content inspires action and connects brands with customers," Adam Kmiec, senior director of mobile, social and content marketing for Walgreens, said. "We believe the Challenged collaboration will be an effective and unique approach to reaching a key consumer audience and driving omni-channel conversions."
keyboard_arrow_downCOMMENTS

Leave a Reply

No comments found

TRENDING STORIES

Polls

Which area of the industry do you think Amazon's entry would shake up the most?