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Gilead, Boehringer Ingelheim ink license agreement

BY Allison Cerra

FOSTER CITY, Calif., and INGELHEIM, Germany — Gilead Sciences has signed an agreement with Boehringer Ingelheim to gain exclusive worldwide rights to research, develop and commercialize BI’s novel anti-retroviral compounds.

Under the terms of the agreement, Gilead will pay the German drug maker an upfront payment and possibly will receive additional payments based upon the achievement of certain development, regulatory and commercial milestones, as well as royalties on future net sales, the companies said.

The class of compounds, known as noncatalytic site integrase inhibitors (NCINIs), target the key component of the HIV virus responsible for incorporation of the viral DNA into the human genome, Gilead and BI said.

"We are very pleased to have established this licensing agreement. The Boehringer Ingelheim compounds complement our internal discovery programs and the efforts are aligned with our commitment to continue to innovate in the field of HIV," Gilead EVP research and development and chief scientific officer Norbert Bischofberger said. "We are looking forward to progressing BI 224436 or other compounds further into clinical development."


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Favorites emerging with latest toy list from Target

BY Gail Hoffer

MINNEAPOLIS — Target is the latest in a line of retailers to put out a list of what it thinks will be the top toys of the holiday season. Many of Target’s hottest toys, including FIJIT friends and the LeapFrog branded LeapPad, are also on toy lists for Toys"R"Us, Kmart and Walmart.

“The holiday season is a busy time of year and our guests are looking for gifts that will make wishes come true,” Target VP toys Stephanie Lucy said. “Target has all of the toys that kids will love, and with our expanded Toy Catalog, it’s easier than ever for gift-givers to make their choices and save at the same time.”

Although it may be a toy list latecomer, Target is going after the competition with the launch of ane expanded toy catalog. Available on Nov. 1., the catalog features eight more pages than last year, as well as a coupon insert that contains more than $350 in savings. To help busy parents stay organized during the holiday season, the toy catalog focuses on list building — complete with checkboxes next to every item, and a special tear-out list for kids to complete, the company reported.

Target’s top toys include:

  • FIJIT Friends

  • Barbie Printable Hairtastic

  • Monster High Doll 5-pack (Target exclusive)

  • Flying Fairies Doll (Target exclusive)

  • Lite Sprites Wand and Sprite

  • Disney My First Princess Doll and Toddler Dress Gift Set (Target exclusive)

  • Lalaloopsy Crumb’s Bake off- Doll with Kitchen Set (Target exclusive)

  • Nerf Vortex Nitron Blaster

  • Star Wars Ultimate FX LightSaber

  • Air Hogs Hyperactives RC Vehicle

  • Paper Jamz Pro Series Mic

  • Disney Cars 2 Charge Ups Charge ‘N’ Race Speedway (Target exclusive)

  • Lego Millennium Falcon

  • Imaginext T-Rex

  • Thomas and Friends Trackmaster Cranky and Flynn Save the Day

  • Top Toys and Games for All:

  • Games: Scrabble, Simon and Yahtzee Flash

  • Disney Hedbanz (Target exclusive)

  • Bop It! XT

  • Rock On Elmo

  • LeapFrog LeapPad

  • Elf on the Shelf Book

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Merck chairman announces retirement

BY Alaric DeArment

WHITEHOUSE STATION, N.J. — Merck chairman Richard Clark is retiring, the company said Thursday.

Merck announced that Clark, who remained chairman of the company after stepping down as president and CEO in 2010, would retire from the company and its board of directors as of Dec. 1. Kenneth Frazier took over as president and CEO in January 2011, and the board has elected him to serve as chairman following Clark’s departure.

"I’ve been a part of Merck for more than 39 years — I always have and always will consider Merck to be an important part of my life and my extended family," Clark said. "It has been a great pleasure to work with the talented, dedicated people of Merck who are so committed to our mission of saving and improving lives around the world."


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