HEALTH

Cardiac issues seen in patients with poorly controlled diabetes

BY Michael Johnsen

ALEXANDRIA, Va. A study included in the May 2009 journal Diabetes Care, a journal published by the American Diabetes Association, demonstrated preclinical abnormalities of cardiac structure and function in adolescent girls with Type 2 diabetes, despite the short duration of diabetes.

The learnings highlight the potential high cardiovascular risk occurring in adolescent Type 2 diabetes, the authors concluded.

As part of the research, 19 adolescent girls were recruited, eight with Type 2 diabetes and 11 with Type 1 diabetes, from a hospital diabetes service and 20 control subjects without diabetes from the schools of the diabetic subjects.

The groups were similar in age and height, but significant differences in body composition were observed. Subjects with Type 2 diabetes had larger left ventricular dimensions and left ventricular mass, which persisted when indexed to height. Diastolic filling was impaired in both diabetic groups, and systolic longitudinal function was lower in the Type 2 diabetic group. Half of the group with Type 2 diabetes met the published criteria for LVH and left ventricular dilatation; 25% had evidence of elevated left ventricular filling pressure in association with structural abnormalities.

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HEALTH

SDI: Rx antivirals drop close to 60%

BY Michael Johnsen

PLYMOIUTH MEETING, Pa. SDI’s Vector One: National shows that for the week ended May 8, the number of new antiviral prescriptions dispensed at retail pharmacies was 118,578 — a 59% drop compared with approximately 277,000 new prescriptions the week before.

Tamiflu accounted for 90% of the market’s new prescriptions last week, SDI stated Tuesday

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PAD patients that use aspirin reduce risk of stroke, study finds

BY Michael Johnsen

CHICAGO In patients with peripheral artery disease, a blocked leg blood vessel, prophylactic use of aspirin either alone or in conjunction with dipyridamole did not reduce incidence of heart disease, but did reduce the risk of a nonfatal stroke, research published May 13 in the Journal of the American Medical Association has found.

The finding comes from a meta-analysis of studies around aspirin use with PAD.

Overall, studies found a 12% reduction in all cardiovascular events among patients receiving aspirin therapy, compared with those who were not. And while that reduction was considered statistically insignificant, the incidence of nonfatal stroke was 34% lower in the aspirin-taking group.

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